|The potential use of antimicrobial surface coatings ranges from medicine, where medical device infection is associated with significant healthcare costs, to the construction industry and the food packaging industry. Thin films containing silver nanoparticles have been seen as promising candidate coatings. Silver is known as one of the oldest antimicrobial agents. Silver ions are thought to inhibit bacterial enzymes and bind to DNA. Silver nanomaterials have been used effectively against different bacteria, fungi and viruses (see for instance: "Antibacterial nanotechnology multi-action materials that work day and night").|
|Using something like an advanced form of a rubber stamp, scientists have now developed a way to adhere an ultra-thin (just a few molecules thick) antibacterial coating to a wound. The "stamped" area shows bactericidal activity for at least 48 hours.|
|Reporting their findings in a recent paper in Advanced Functional Materials ("Polymeric Multilayers that Contain Silver Nanoparticles can be Stamped onto Biological Tissues to Provide Antibacterial Activity"), a research team from the University of Wisconsin-Madison, led by Nicolas Abbott, describes a process for creating a transparent ultra-thin polymer coating carrying precise loads of silver nanoparticles.|
|A key innovation underlying the approach presented in this paper is a procedure that permits the mechanical transfer of pre-fabricated polymer thin films onto soft-biological tissue such as skin dermis (serving as a skin wound simulant).|
Sunday, November 20, 2011
Stamping antibacterial nanoparticles onto wounds
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