The synthesis of N–Zn, N–Cu complexes involving 2-amino pyridine
and ethylenediamine ligands and application to the Henry reaction.
N–Zn and N–Cu complexes occupy an important position in organometallic chemistry. They have been reported in many literature.
For example, as catalysts, they have shown high activities in organic reactions and polymerizations.
Inspired by this work, we first synthesized novel N–Zn, N–Cu complexes with a simple, one-pot method , and the crystal structures of 1a, 1b, 2a and 2b were obtained and were also characterized by NMR, IR and elemental analysis. The Henry reaction, or the nitroaldol reaction, is an important organic reaction for constructing C–C bonds. For example, it allows access to intermediate functionalized structure motifs , such as 1,2-amino
alcohol and α-hydroxy carboxylic acids. Many literature reports have detailed these synthetic methods. A major question that needs to be addressed is how to obtain the products in an efficient way.
More information: http://www.ias.ac.in/chemsci/Pdf-Jul2009/435.pdf